As the title suggests I walked into the office this morning to two computers…both shut off. Now no one touches my desk especially when I have analysis running and we had a huge storm last night with lightening and wind and although Bangkok is a ‘1st’ world entity of itself some days the fact of the matter is, I live in a 3rd world country that is 98% agriculture. The result?

So in the world of molecular evolution one of the cu-de-gras-de-analysis programs would have to be BEAST. A power-packed bayesian analysis software that makes phylogenetic trees, calculates the time to the most recent common ancestor (tMRCA) and substitution rates, geographic partitioning, can handle copious amounts of data and pretty much squeezes blood from a turnip…walks on water…heals your mother, in short, it’s cool.

Sound awesome? It is. For a more technical in depth discussion and introduction to BEAST software I suggest reading the Wiki and attacking the tutorials with full force as well as reading some awesome books on phylogenetic inference such as The Phylogenetic Handbook. If you are super impatient and channeling your inner terrible twos about phylogenetic analysis then read Phylogenetic Trees Made Easy. It has a nice introduction and literal button for button how tos on different software packages including Bayesian ones. When you’ve finished your tantrum, enter the adult world and read Felsenstein or the phylogenetic handbook mentioned above. Now that you’ve been introduced to phylogenetic inference and genetic analysis with forays into evolution over time…jump into BEAST. Although the BEAST wiki and manual are still navigate-able without that background but you’ll be scratching your head a bit and heading to google for answers.